Clinical Practice Guidelines for CLOVES Syndrome - Vascular Anomalies Center, Boston Children's Hospital
Imaging Guidelines for Vascular Anomalies developed by Children's Hospital Boston - Guidelines for imaging with MRI, ultrasound, CT and angiogram when indicated.
Recommended Kidney Screening for children with CLOVES - Recommended screening guidelines for children with CLOVES, developed February 2012
The Vascular Anomalies Center team at Children’s Hospital Boston recently became aware of three cases of Wilms Tumor in young patients with CLOVES syndrome. While Wilms tumor has been associated with some overgrowth related disorders, such as Beckwith-Wiedemann Syndrome, it is a new finding in patients with CLOVES syndrome.
Our recommendation for Wilms tumor screening is serial ultrasounds performed every three months up to age 8 years after which there is not thought to be any increased risk of developing Wilms tumor. We have also chosen to notify families and physicians of CLOVES syndrome patients between the ages of 8 and 12 years so that they may decide whether to obtain a single ultrasound to rule out late development of Wilms tumor.
Questions may be addressed to your child’s pediatrician or to the Vascular Anomalies Center, Children’s Hospital Boston, at 617-355-5226. This information is also on the Vascular Anomalies Center CHB website.