PIK3CA Related Conditions Research Roundtable

Join the PIK3CA Related Conditions Research Roundtable:

As part of the development of the Patient-Led Collaborative Research Network for PIK3CA Related Conditions (PROS), CLOVES Syndrome Community is launching a new opportunity and space for researchers to connect, share and learn from one another.

Our Research Roundtable will meet every other month and will focus on knowledge exchange, feedback on ongoing projects, sharing work and research in progress.  The Research Roundtable will be moderated by Ralitsa Madsen (Sir Henry Wellcome Fellow, UCL Cancer Institute, UK). Each meeting will feature one 20-minute presentation, with time for questions and discussion, for a total of one hour.

This roundtable is for:

  • Basic and pre-clinical researchers in academia and industry 
  • Graduate students
  • CLOVES Syndrome Community funded research grantees
  • Patient advocacy organization leaders

Goals of the roundtable: 

  • To accelerate progress in basic PROS research through open knowledge exchange
  • To enable PROS researchers to share positive as well as null results independent of formal publication venues
  • To enable PROS researchers to get feedback on ongoing or planned projects, akin to an international “lab meeting” 
  • To foster international collaboration among PROS researchers

Expectations of group members:

  • Active participation (80% attendance)
  • Commitment to minimum one presentation each year
  • Commitment to share ongoing work independent of publication 
  • This is a closed-door conversation. All information shared within this meeting is considered confidential unless otherwise specified.

You must register for the roundtable here


Past Roundtable Presenters

Dr. Benoit Bilanges, UCL Cancer Institute
“A small molecule activator of PI3Kalpha, a new tool to probe PI3K signalling and biology”

Sandra Castillo, Carreras Research “PIK3CA-driven vascular malformations”

Sarah Sheppard, NIH – “PIK3CA is the most common cause of vascular malformations in a cohort of 356 participants”

Dr. Wen Yi Aw, PhD – UNC Chapel Hill – “Microphysiological modeling of PIK3CA-driven vascular malformations”

Colin Ratcliffe, PhD – The Francis Crick Institute – “Imaging response to Akt kinase inhibition in 3D models”

Elisa Boscolo, Boscolo Lab and Dr. Adrienne Hammill, MD PhD – Cincinnati Children’s Hospital

Dr. Romuald Girard -“PIK3CA gain of function, a new insight in cerebral cavernous malformation pathogenesis”.

Ralitsa Madsen – Establishing MADR-based cell models for systems biology studies of PIK3CA activation

Emily Erickson , Toker Lab  – Targeting the PI3K/AKT pathway using pan-AKT degraders

Ana Angulo-Urarte – PIK3CA Variants in PROS